Publications are listed by topic. Some are crosslisted, where applicable. Group member's names are in bold. All publications are available as pdf files.

Influenza

Catherine AA Beauchemin and Andreas Handel (2011) "A review of mathematical models of influenza A infections within a host or cell culture: lessons learned and challenges ahead", BMC Public Health 11 (Suppl 1):S7

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2010) "Towards a quantitative understanding of the within-host dynamics of influenza A infections", Journal of the Royal Society Interface 7, 35-47

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2009) "Intervention strategies for an influenza pandemic taking into account secondary bacterial infections", Epidemics 1, 185-195

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2009) "Antiviral resistance and the control of pandemic influenza: The roles of stochasticity, evolution and model details", Journal of Theoretical Biology 256 (1), 117-125

Andreas Handel and Rustom Antia (2008) "A Simple Mathematical Model Helps To Explain the Immunodominance of CD8 T Cells in Influenza A Virus Infections", Journal of Virology 82 (16), 7768-7772

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2007) "Neuraminidase Inhibitor Resistance in Influenza: Assessing the Danger of its Generation and Spread", PLoS Computational Biology 3 (12): e240

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2007) "What is the best control strategy for multiple infectious disease outbreaks?", Proceedings of the Royal Society B 274, 833-837

Cecile Viboud, Theresa Tam, Douglas Fleming, Andreas Handel, Mark A. Miller, Lone Simonsen (2006) "Transmissibility and mortality impact of epidemic and pandemic influenza, with emphasis on the unusually deadly 1951 epidemic", Vaccine 24, 6701

Drug Resistance

Andreas Handel, Elisa Margolis, Bruce R. Levin (2009) "Exploring the role of the immune response in preventing antibiotic resistance", Journal of Theoretical Biology 256 (4), 655-662

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2009) " Antiviral resistance and the control of pandemic influenza: The roles of stochasticity, evolution and model details", Journal of Theoretical Biology 256 (1), 117-125

Andreas Handel, Roland R. Regoes, Rustom Antia (2006) "The Role of Compensatory Mutations in the Emergence of Drug Resistance", PLoS Computational Biology 2(10): e137
Correction of some typos in the original paper.

Within-host dynamics

Jessica Moffat, Andreas Handel, Peter Doherty, Stephen Turner, Paul Thomas, Nicole La Gruta (2010) "Influenza Epitope-Specific CD8+ T Cell Avidity, but Not Cytokine Polyfunctionality, Can Be Determined by TCRb Clonotype", Journal of Immunology 185, 6850-6856

Andreas Handel, Andrew Yates, Sergei S. Pilyugin, Rustom Antia (2009) "Sharing the burden: Antigen transport and firebreaks in immune responses", Journal of the Royal Society Interface 6, 447-454

Andreas Handel, Elisa Margolis, Bruce R. Levin (2009) "Exploring the role of the immune response in preventing antibiotic resistance", Journal of Theoretical Biology 256 (4), 655-662

Andreas Handel and Rustom Antia (2008) "A Simple Mathematical Model Helps To Explain the Immunodominance of CD8 T Cells in Influenza A Virus Infections", Journal of Virology 82 (16), 7768-7772

Andreas Handel, Andrew Yates, Sergei S. Pilyugin, Rustom Antia (2007) "Gap junction-mediated antigen transport in immune responses", Trends in Immunology 28, No. 11, 463-466

Epidemiological Control

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2009) "Intervention strategies for an influenza pandemic taking into account secondary bacterial infections", Epidemics 1, 185-195

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2009) " Antiviral resistance and the control of pandemic influenza: The roles of stochasticity, evolution and model details", Journal of Theoretical Biology 256 (1), 117-125

Andreas Handel, Ira M. Longini Jr., Rustom Antia (2007) "What is the best control strategy for multiple infectious disease outbreaks?", Proceedings of the Royal Society B 274, 833-837

Microbial Evolution

Andreas Handel and Daniel E. Rozen (2009) "The impact of population size on the evolution of asexual microbes on smooth versus rugged fitness landscapes", BMC Evolutionary Biology 9:236

Andreas Handel and Matthew R. Bennett (2008) "Surviving the bottleneck: Transmission mutants and the evolution of microbial populations", Genetics 180 (4), 2193-2200

Daniel E. Rozen, Michelle G. J. L. Habets, Andreas Handel, J. Arjan G. M. de Visser (2008) "Heterogeneous Adaptive Trajectories of Small Populations on Complex Fitness Landscapes", PLoS One 3 (3): e1715

Influenza

Drug Resistance

Within-host dynamics

Epidemiological Control

Microbial Evolution

Other Topics